Genomic analysis links K5 capsule to phage susceptibility in uropathogenic E. coli

This study analyzes 49 ESBL-producing uropathogenic Escherichia coli (UPEC) isolates and 42 phages to identify bacterial genomic features linked to phage susceptibility. The research highlights the role of K5 capsule biosynthesis genes as a key factor influencing phage susceptibility, which could aid in selecting effective phages for treating infections caused by antibiotic-resistant UPEC strains.

Originally published by gnews