Danshensu reduces type 2 diabetes-related osteoporosis via PI3K/AKT/Nrf2 pathway

Danshensu reduces type 2 diabetes-related osteoporosis via PI3K/AKT/Nrf2 pathway

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This study investigates the effects of Danshensu (DSS), a compound derived from Salvia miltiorrhiza, on osteoporosis related to type 2 diabetes (T2DOP). Using mouse models and cellular experiments, DSS was found to improve bone microarchitecture and reduce bone loss, potentially through the PI3K/AKT/Nrf2 signaling pathway. These findings suggest DSS may have therapeutic potential for managing T2DOP.

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Originally published by gnews