Cancer-promoting proteins YAP/TAZ linked to tumor visibility and immune evasion

Researchers at Hiroshima University and international collaborators have found that the cancer-promoting proteins YAP and TAZ are associated with genomic instability that may make tumors more recognizable to the immune system. However, these proteins also increase PD-L2 levels, which help cancer cells evade T-cell attacks. This dual role highlights a complex interaction between tumor visibility and immune suppression.

Originally published by gnews